Vascularization: Regenerative Medicine and Tissue Engineering

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Discover the best of shopping and entertainment with Amazon Prime. Prime members enjoy FREE Delivery on millions of eligible domestic and international items, in addition to exclusive access to movies, TV shows, and more. Back to top. Get to Know Us. English Choose a language for shopping. Audible Download Audio Books. Alexa Actionable Analytics for the Web. Cell Transplant. Cell-microenvironment interactions and architectures in microvascular systems. Biotechnol Adv. Vascularization of three-dimensional engineered tissues for regenerative medicine applications.

Acta Biomater. Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues. Bioengineered cardiac cell sheet grafts have intrinsic angiogenic potential. Biochem Biophys Res Commun. In vivo vascularization of cell sheets provided better long-term tissue survival than injection of cell suspension.

J Tissue Eng Regen Med. Engineering vascularized skeletal muscle tissue. Nat Biotechnol. Vascularized and functional human liver from an iPSC-derived organ bud transplant. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Three-dimensional cell-dense constructs containing endothelial cell-networks are an effective tool for in vivo and in vitro vascular biology research.

Microvasc Res. Design of prevascularized three-dimensional cell-dense tissues using a cell sheet stacking manipulation technology.

About this Research Topic

Comparison of angiogenic potential between prevascular and non-prevascular layered adipose-derived stem cell-sheets in early post-transplanted period. J Biomed Mater Res A. Atherogenic cytokines regulate VEGF-A-induced differentiation of bone marrow-derived mesenchymal stem cells into endothelial cells. Stem Cells Int. Caplan AI, Correa D.

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The MSC: an injury drugstore. Cell Stem Cell. Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. The role of macrophage phenotype in vascularization of tissue engineering scaffolds. Human mesenchymal stromal cells attenuate graft-versus-host disease and maintain graft-versus-leukemia activity following experimental allogeneic bone marrow transplantation. Stem Cells.

First 3D Engineered Vascularized Human Heart Is Bioprinted

Principals of neovascularization for tissue engineering. Mol Asp Med. Chiu LL, Radisic M. Scaffolds with covalently immobilized VEGF and Angiopoietin-1 for vascularization of engineered tissues. VEGF expression in mesenchymal stem cells promotes bone formation of tissue-engineered bones. Mol Med Rep. Tayalia P, Mooney DJ. Controlled growth factor delivery for tissue engineering. Adv Mater.

Roles of vascularization and innervation in regenerative medicine - Jonathan Grasman

Coadministration of adipose-derived stem cells and control-released basic fibroblast growth factor facilitates angiogenesis in a murine ischemic hind limb model. J Vasc Surg. Langer R, Vacanti JP. Tissue engineering. Engineering vessel-like networks within multicellular fibrin-based constructs.

Cell tri-culture for cardiac vascularization. Methods Mol Biol. A biodegradable vascularizing membrane: a feasibility study. Development of vascularized iPSC derived 3D-cardiomyocyte tissues by filtration layer-by-layer technique and their application for pharmaceutical assays. Shimizu T. Cell sheet-based tissue engineering for fabricating 3-dimensional heart tissues.

Circ J. Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro. Nat Protoc. Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis. Cellular control of tissue architectures using a three-dimensional tissue fabrication technique. Micro-patterned cell-sheets fabricated with stamping-force-controlled micro-contact printing. Patterning of two-level topographic cues for observation of competitive guidance of cell alignment.

Vascularization Regenerative Medicine and Tissue Engineering

Mir TA, Nakamura M. Three-dimensional bioprinting: toward the era of manufacturing human organs as spare parts for healthcare and medicine. Tissue Eng Part B Rev. Regeneration and experimental orthotopic transplantation of a bioengineered kidney. Nat Med. The effect of detergents on the basement membrane complex of a biologic scaffold material. Endothelial cell self-fusion during vascular pruning. PLoS Biol. Treatment of large bone defects with a vascularized periosteal flap in combination with biodegradable scaffold seeded with bone marrow-derived mononuclear cells: an experimental study in rats.

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Tissue Eng Part A. Automatic quantitative micro-computed tomography evaluation of angiogenesis in an axially vascularized tissue-engineered bone construct. Tissue Eng Part C Methods. In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels. Nat Commun.