EMBOSS Developers Guide: Bioinformatics Programming

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Its application in distributed environments, such as the internet, electronic commerce, environment monitoring, mobile communications, wireless devices, distributed computing, to mention only a few, is continuously increasing, becoming.. Read More. Price incl. Local courier delivery with tracking number or collect from 90 lockers islandwide.

Add to My List. Added to Cart. Protein structure is complex trajectory in 3D space and it can be ab-stracted into a polygonal curve. Capturing structural properties from the Cartesian coordinates of thousands of atoms is an important step in performing structural analysis such as similarity detection and defining patterns. The objective of this research is to investigate the potential use of some knot theoretic quantities such as self-linking, R30 invariants and HEO vector for structural Bioinformatics applications.

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The work presented suggests that self-linking writhing can be used to identify a-helices. A revised sliding window approach together with 2 curve simplification methods were emp.. Bioinformatics Analyses of Alternative Splicing. This thesis investigates three aspects of alternative splicing by means of computational large-scale analyses. In the first part, we introduce a new approach for the ab initio prediction of alternative splice events.

We introduce an efficient algorithm to reduce the computational complexity during the search for new splice events. Applying this algorithm to the human genome, we predict and verify novel splice events.


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In the second part, we investigate the influence of mRNA secondary structures on the regulation of the splicing process. We show that experimentally verified binding sites of splicing regulatory proteins have a higher single-strandedness. Then, we d..


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Gamma-secretase is an enzymatic complex critical to amyloid formation and other important pathophysiological processes. Non-specific gamma-secretase inhibitors are not ideal for intervention of familial Alzheimer's disease. Also gamma-secretase cleaves a variety of substrates. But different sites are cleaved even in a single substrate and no consensus sequence for cleavage by gamma-secretase is identified. We hypothesize that consensus compositional sequence in components of gamma-secretase and its substrates should exist during gamma-secretase regulation and specific gammasecretase inhibitor based on such consensus sequence may act as a therapeutic intervention..

Roerdink, Jos B. The 9th ISMM conference covered a very diverse collection of papers, bound together by the central themes of mathematical morphology, namely, the tre- ment of images in terms of set and lattice theory. Notwithstanding this central theme, this ISMM showed increasing interaction with other?

This trendis particularlystrong in the emerging? This build..

EMBOSS -- A One-Stop-Shop for Basic Bioinformatics Analysis

This textbook presents mathematical models in bioinformatics and describes biological problems that inspire the computer science tools used to manage the enormous data sets involved. The first part of the book covers mathematical and computational methods, with practical applications presented in the second part. The mathematical presentation avoids unnecessary formalism, while remaining clear and precise. The book closes with a thorough bibliography, reaching from classic research results to very recent findings.

This volume is suited for a senior undergraduate or graduate course on bioinformatics, with a strong focus on mathematical and computer science backgr.. Sosik, Petr. During the last 14 years the DNA C- puting meetings have been the key forum at the boundary between computer science, biochemistry and nanotechnology where the most recent results have been presented and their authors have met.

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Their scienti? It continues to be one of the most exciting interdisciplinary meetings, as exempli? Theory and Mathematical Methods in Bioinformatics. Bioinformatics is an interdisciplinary science which involves molecular bi- ogy, molecular chemistry, physics, mathematics, computational sciences, etc. Mostofthebooksonbiomathematicspublishedwithinthepasttenyearshave consistedofcollectionsofstandardbioinformaticsproblemsandinformational methods, andfocus mainly onthe logisticsofimplementing andmakinguse of various websites, databases, software packages and serving platforms.

While these types of books do introduce some mathematical and computational methods alongside the software packages, they are lacking in a systematic and professional treatment of the mathematics behind these methods. It is signi? Bioinformatics: Problem Solving Paradigms. What is this book good for? Imagine you are a computer scientist working in the bioinformatics area. In order to set up a list of libraries that you have access to, you must first login or sign up. Then set up a personal list of libraries from your profile page by clicking on your user name at the top right of any screen.

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Separate different tags with a comma. To include a comma in your tag, surround the tag with double quotes. Please enable cookies in your browser to get the full Trove experience. Skip to content Skip to search. Language English View all editions Prev Next edition 1 of 2. Molecular biology -- Computer programs. It includes over applications for molecular sequence analysis and other common tasks in bioinformatics.

About this book

It integrates the core applications with a range of popular third party software packages under a consistent and powerful command line interface. The software has many useful features; for example, it automatically copes with data in a variety of formats and allows for transparent retrieval of sequence data from the web"-- Contents Machine generated contents note: Acknowledgements; Preface; 1. Conventions; 2. Getting started; 4.

A complete application; 7.

Evolving Connectionist Systems

ACD file development; 8. C programming; 9. Programming with AJAX; Incorporating third-party applications; ACD syntax reference; AJAX library reference; Notes Includes bibliographical references and index. Online version of the print title.

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